A generalized inflammatory cutaneous disorder characterized by erythema and exfoliation. The scales are also tender and dry after the skin has peeled off. include protected health information. Than l started to do some research on skins conditions and what l have founed is that allmost all of them are not caused by external factors but rather internal . By Mayo Clinic Staff. Contact Dermatitis. is it lighter than usual. It may be more common in those with with sweaty palms, i.e. Sign up for free, and stay up to date on research advancements, health tips and current health topics, like COVID-19, plus expertise on managing health. The thumb on my left hand has even less peeling than my right hand, and it hardly looks effected at all. 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). These agents modulate inflammatory and immune responses. Toxic shock syndrome (TSS). American College of Occupational and Environmental Medicine, American Society for Dermatologic Surgery, University of Arkansas for Medical Sciences College of Medicine. Int J Dermatol. For an accurate diagnosis of exfoliative keratolysis, a negative result from a patch test is required. Advertising revenue supports our not-for-profit mission. With her unique perspective and engaging writing style, Beckley is a must-read for anyone interested in the world of beauty and fashion. Then I started taking hyaluronic acid for knee pain and my symptoms completely disappeared. Dr. Hirsch names exfoliative keratolysis, a condition that manifests as blisters and peeling of the skin on the palms and fingers, as a cause of peeling fingertips. Advising patients to drink plenty of fluids and to eat a high-protein diet is a good way to keep their fluid and protein levels stable. The majority of respondents thought the following sentence was incorrect: 119 (1):38-44. Shim TN, Berth-Jones J. Erythroderma. Mayo Clinic College of Medicine and Science, Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Graduate Medical Education, Mayo Clinic School of Continuous Professional Development, Mayo Clinic on Incontinence - Mayo Clinic Press, NEW Mayo Clinic on High Blood Pressure - Mayo Clinic Press, Mayo Clinic on Hearing and Balance - Mayo Clinic Press, FREE Mayo Clinic Diet Assessment - Mayo Clinic Press, Mayo Clinic Health Letter - FREE book - Mayo Clinic Press, Financial Assistance Documents Minnesota, Mayo Clinic Minute: Moisturizer tips from a dermatologist. I have very thick skin from working my whole life, and no hand creams even touch this EK. Severe symptoms of exfoliative dermatitis can cause life-threatening complications, including: In some rare cases, exfoliative dermatitis can be fatal, typically as a result of pneumonia, septicemia, or heart failure. adams county sheriff news 234-38. WebFor many years I thought I had exfoliative keratolysis. Some effective essential oils include ginger oil, clove oil, myrrh oil, lavender oil, and frankincense oil. Treatment of Skin Disease: Comprehensive Therapeutic Strategies. Coconut Shampoo: A Natural Way To Darken Gray Hair? Exfoliative keratolysis is an autoimmune disorder characterized by the shedding of the top layer of skin. Massive peeling and scaling, often white or yellowish, follows this discoloration and inflammation. Photochemotherapy a technique used to boost the immune system. Exfoliative keratolysis is a skin condition where there is frequent focal skin peeling on the palms of the hands, the surface of the fingers, and, less often, on the soles of the feet. information submitted for this request. My palms looked horrible, and would cycle in and out of major peeling (1.5 weeks of peeling, 1 week of decent skin.) Sign Up for the Latest Health News and Tips, Home Skin Care What Is Exfoliative Keratolysis? Though it looks like dry, peeling skin, water makes it worse. It is one of the rarest diseases which is also known as skin peeling disease. Mark Louden, MD Assistant Professor of Clinical Medicine, Division of Emergency Medicine, Department of Medicine, University of Miami, Leonard M Miller School of Medicine However, this past year (after much trial and error) I finally found something that treats the symptoms with about 95%. AskMayoExpert. He is an assistant professor at the Downstate Health Sciences Center at the State University of New York. Chikunpu is a Papulerythroderma that responds to cyclosporin treatment. Diagnosis is depending on the clinical features, family history, personal history, and lab tests. Neonatal desquamation (child). Tryed every emollient cream outhere including corticosteroids. Peeling skin syndrome (PSS) Peeling skin syndrome is a genetic affliction in which your skin chronically peels. Kawasaki disease (child). Pemphigus is a potentially lethal autoantibody driven Its by LUSH cosmetics. Conditions that may cause skin peeling include: Specific diseases and conditions that can cause peeling skin include: Causes shown here are commonly associated with this symptom. @Mia Accessed April 5, 2022. Required fields are marked *. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. Mahajan VK, Singh R, Mehta KS, Chauhan PS, Sharma S, Gupta M, et al. The development of exfoliative dermatitis may relate to how skin cells and white blood cells interact with the immune system, which then produces the major increase in skin cell turnover. Non-IgE-mediated drug sensitivity. information and will only use or disclose that information as set forth in our notice of Had for years If you have scalp eczema, psoriasis, or dermatitis, you may lose 7.2 g, 9.6 g, and 22.6% of your scale daily. The reaction may start as a rash before developing into exfoliative dermatitis. WebExfoliative dermatitis, also known as erythroderma, is an uncommon but serious skin disorder that family physicians must be able to recognize and treat appropriately. All l did was to take probiotics and Indian herbal antibiotic which is an excellent blood purifier ! I can safely say now however that I have not had this happen in a year from performing one simple routine. David Vearrier, MD, MPH Professor of Emergency Medicine, Department of Emergency Medicine, University of Mississippi Medical Center Exfoliative dermatitis, generalized; Generalized exfoliative dermatitis; Ritter's disease (L00); Hebra's pityriasis. Seborrheic dermatitis. Peeling skin syndromes (PSSs) are a heterogeneous group of rare, autosomal recessive disorders characterized by superficial, painless peeling and blistering of the skin without mucosal fragility [ 1-3 ]. So l started taking care of my intestinal flora and after only 2 months my skin improved faster and better than in 3 years after using tens of emollients and corticosteroids. out whether it is a genetic mutation regarding bile acid production, or melatonin dysfunction. Mayo Clinic; 2022. 2. There is no definitive cure for exfolaitive keratolysis; however, the right treatments can help control symptoms of the condition, such as lactic acid application, ultraviolet radiation treatment, or home remedies like certain essential oils or a coconut oil moisturizer. Sometimes it peels off so deeply that it makes me bleed. I could literally peel sheets of skin off my palm. Your nails may take on a dull appearance, thicken, become brittle, and develop ridges. This website also contains material copyrighted by 3rd parties. Does tea tree oil help any of this? Keratolysis exfoliativa (KE) is a palmoplantar eruption of air-filled bullae on an erythematous base, which results in lamellar peeling with hallmark superficial Neonatal desquamation (child). If you log out, you will be required to enter your username and password the next time you visit. There is no definitive answer to this question as the condition can vary in severity from person to person. Contact Dermatitis. To enhance improvement, add a few drops of anti-inflammatory essential oils to the hand bath. Most people with exfoliative dermatitis also feel generally ill. [QxMD MEDLINE Link]. Repeated irritation can lead to skin peeling. Autoimmune blistering diseases (AIBD) are paradigms of autoantibody-mediated organ-specific autoimmune disorders that involve skin and/or mucous membranes. Photochemotherapy a technique used to boost the immune system. Exfoliative keratolysis is not a disease that aggravates to such a condition that may cause a threat to life. By maintaining proper lifestyle and avoiding the irritants, the pain or tenderness of this skin condition can be reduced. Genetic disease, including a rare skin In babies born past their due date, it's not unusual for them to experience some painless skin peeling. Lets take a deeper look at some of the other exfoliative keratolysis treatments available. Work with your doctor or other health care professional for an accurate diagnosis. AskMayoExpert. Generalized exfoliative ichthyosiform erythroderma which is often fatal in neonatal period, usually converts into ichthyosis linearis circumflexa. WebPain. Mayo Clinic does not endorse companies or products. While eczema and exfoliative keratolysis look very similar, the difference is that exfoliative keratolysis will peel and shed, whereas eczema also produces itchy skin. Mayo Clinic; 2021. Keratolysis exfoliativa, as a self-limiting condition, can be treated. Your care team will first work to address dehydration, low blood volume, heat loss, and electrolyte or nutritional deficiencies. Exfoliative keratolysis magnesium oxide. Background Keratolysis exfoliativa (KE), also known as dyshidrosis lamellosa sicca, is a palmoplantar dermatosis characterized by air-filled blisters and collarette desquamation. All rights reserved. If you do have symptoms of this condition, its best to get the right diagnosis from a healthcare professional so that they can help you identify potential triggers. Mayo Clinic does not endorse companies or products. They may: Your care team will also offer support with managing any underlying conditions. Exfoliative keratolysis is a skin condition where there is frequent focal skin peeling on the palms of the hands, the surface of the fingers, and, less often, Its main characteristics are red, dry, and peeling skin. [QxMD MEDLINE Link]. It usually happens when the palms, fingers, or feet become dry, which makes the skin rough and leads to the peeling of skin from the hand or feet. If you are a Mayo Clinic patient, this could R boggs construction. Elsevier Limited; 2012. Other important goals of exfoliative dermatitis treatment include reducing inflammation and making you more comfortable, so supportive care could involve: The outlook for exfoliative dermatitis can vary, depending on whats causing the reaction. Exfoliative Dermatitis Medication: Corticosteroids, Antihistamines, Immunosuppressives, Antirheumatic, Disease Modifying Drugs & Diseases > There is no current FDA approval/indication for the use of this drug with exfoliative dermatitis. Review/update the I have wondered if this problem arises from not enough fatty acids in my diet. Treatment for exfoliative keratolysis focuses on relieving the symptoms. Exfoliative dermatitis. Ultraviolet radiation treatment is also called photochemotherapy (PUVA), and uses ultraviolet rays to treat exfoliative keratolysis. Med Chir Med Soc Nat Iasi is an abbreviation for Rev Med Chir Med Med Nat Iasi. If you do not take it, you may not only have skin damage, but your body may also become unable to keep warm. Mayo Clinic; 2021. To provide you with the most relevant and helpful information, and understand which It can also fortify the epidermal barrier that may prevent future exfoliative keratolysis outbreaks. Our experts continually monitor the health and wellness space, and we update our articles when new information becomes available. Exfoliative keratolysis is an excessive peeling of the skin on the palm of the hands and is sometimes called "focal palm peeling." WebTreatments: - Apple Cider Vinegar: First time I tried it, I did it for a week, 10 minutes before going to sleep, and my hand improved drastically and I was very happy with it. I somehow hope that Mike Newcombe could give us an update on his condition and how it worked out for him in the long run, even though his post is from 2012 All named individuals and organisations maintain copyright for the relevant images. WebAcral skin eruption observed during SARS-CoV-2 pandemic: possible keratolysis exfoliativa with red palms and soles. The hand cream can prevent the excessive scales and dryness that lead to peeling from forming. AskMayoExpert. Clinical Clues to Causes of Exfoliative Dermatitis in Adults, Medical history or family history of psoriasis, Withdrawal of corticosteroids, methotrexate, or cyclosporine, Nail pitting, translucent yellow-red nailbed discoloration, onycholysis, Past medical history or family history of atopy such as eczema, allergic rhinitis, or asthma, Recent history of morbilliform or scarlatiniform exanthem, Medication history includes one of implicated drugs, Sharply demarcated islands of sparing ("nappes claires"), Oral medications (systemic contact dermatitis), History of malignancy or lymphoproliferative disorder, Table 2. This content does not have an English version. The inflammatory process involves > 90% of the body surface area. The process takes about two weeks, then just repeats. There is no response to steroid creams and it is not itchy. Having done a lot of reading now, I am starting to suspect this may actually be a different skin condition - exfoliative keratolysis - rather than directly caused by thyroid hormone imbalance. Once you stop the medication and get treatment for your symptoms, your skin will generally clear up within a few weeks. You need to figure look at the color of your faces (secondary bile acids) That said, healthcare professionals can do a lot to manage your symptoms, even when they dont know what causes them. Exfoliative dermatitis, sometimes called erythroderma, involves redness and peeling of the skin over at least 90 percent of the skin on the surface of your body. MedlinePlus. There are also forms of exfoliative keratolysis natural treatment that may help relieve the condition. Finally, I tried using medical grade lactic acid and applying directly to my skin. A medication allergy, for instance, might prove easier to treat than an unknown cause. WebBackground: Keratolysis exfoliativa (KE), also known as dyshidrosis lamellosa sicca, is a palmoplantar dermatosis characterized by air-filled blisters and collarette desquamation. Exfoliative keratolysis can begin as small blisters that turn into a peeling that never really seems to go away or heal. There is no definitive cure for exfoliative keratolysis. Boca juniors domingo 13 de abril 2014. While certain skin conditions, reactions to medication, and some diseases can all cause exfoliative dermatitis, healthcare professionals might not always be able to identify the cause. Int J Dermatol. Exfoliative dermatologic conditions: Suspected SJS, TEN, or DRESS: Withhold; discontinue if not at least partially resolved after 12 weeks on corticosteroid Immune-related AEs commonly present as inflammatory autoimmune reactions and may be managed with supportive care, immune modulation, or corticosteroid treatment, The application of cucumber juice, aloe vera gel, witch hazel, or pineapple juice can also help improve exfoliative keratolysis. A treatment with Docycyline was started. The epidermis is made of several layers of keratina protein necessary for skin strength and flexibility. Also, be sure to clean your hands to keep bacteria from getting inside the cracks on your hands and fingers. As a result, you might experience flu-like symptoms, such as: Widespread skin peeling can also lead to heat loss from your damaged skin. Causes and Treatment. Peeling skin on the hands and feet in children can be caused by direct damage to the skin or by a wide variety of mild to serious diseases, disorders and conditions. Mayo Clinic; 2021. Make your tax-deductible gift and be a part of the cutting-edge research and care that's changing medicine. Autoimmune blistering diseases (AIBD) are paradigms of autoantibody-mediated organ-specific autoimmune disorders that involve skin and/or mucous membranes. Merck Manual Professional Version. Although exfoliative keratolysis is often painless and relatively harmless at times, the appearance of peeled skin may lead to embarrassment and depression. Image Rights - The PCDS would like to thank Dermatoweb, DermQuest (Galderma), and others who have contributed images. By the time Id removed all the baubles etc, my hands were filthy. Some precaution (works for me) Its only my left hand, palm and fingers. Exfoliative dermatitis. Peeling skin may occur because of direct damage to the skin, such as from sunburn or infection. Healthline Media does not provide medical advice, diagnosis, or treatment. I have started using gloves while showering, cut off some water activities and keeping my skin moisturised all of the time. AskMayoExpert. by Beckley Melendez | Oct 13, 2022 | Skincare. Along with the causes of dark, Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. The skin beneath becomes tender, dry and red. Exfoliative dermatitis is a serious skin condition that can be caused by a variety of medications. Dr. Oakley recommends using effective emollient hand creams containing urea or lactic acid to manage the symptoms. Rev Med Chir Soc Med Nat Iasi. I now do at least 2 clinical hand washes each day and the skin on my hands has been perfect ever since! It may also be a sign of an immune system disorder or other disease. Mayo Clinic; 2021. It is unknown why some people get exfoliative keratolysis, but we do know it has something to do with changes in keratin production. AskMayoExpert. Tinea Pedis. Peeling skin (desquamation) is the loss or shedding of the outer layer of your skin (epidermis). According to dermatologist Dr. Amanda Oakley, exfoliative keratolysis starts off as blisters on the fingers of palms. It is This painful or harmless skin problem also goes by names such as keratolysis exfoliativa, lamellar dyshidrosis, dyshidrosis lamellosa sicca, and recurrent palmar peeling. I hope this works for you as well as it has for me. The two major forms are acral peeling skin syndrome (APSS; also called localized PSS) and generalized PSS [ 4-7 ]. Depressed mood. Psoriasis. Lets take a brief look at the possible exfoliative keratolysis causes below: One of the first key exfoliative keratolysis symptoms is air-filled blisters that later peel in a circular pattern, or split and form skin tags. Mark Louden, MD is a member of the following medical societies: American College of Emergency PhysiciansDisclosure: Nothing to disclose. It is also named as Focal palmer peeling, Keratolysis Exfoliativa and dyshidrosis lamellose sicca. There is no proven medication for treating this disorder, but a proper management strategy can provide [Continue Reading] Poison Ivy Rash Your skin might become red, purplish, pink, or light brown. [QxMD MEDLINE Link]. This can ensure that exfoliative keratolysis will not be exacerbated by secondary infections. This is the most common symptom. (1999). These blisters inevitably burst, causing the palm peeling. Keratolysis exfoliativa (also known aslamellar dyshidrosis, recurrent focal palmar peeling, and recurrent palmar peeling) is a sometimes harmless but painful skin condition that causes peeling of the palmar. Eat the proper diet: It is best to eliminate processed foods and additives, fried foods, high-sugar foods, and common food allergens from the diet. Your email address will not be published. These triggers lead your skin cells to turn over, or Paroxetine. The sites affected are palms, soles and fingers. Pain in Hair Roots Trichodynia Its Causes and Treatment, Rash in Corner of Mouth: Angular Cheilitis and its Treatment, Heat rash in Babies: Best ways to Treat and Prevent, Eight Signs of Malignant Melanoma: The ABCDE Rule, Itchy Arms No Rash: Brachioradial Pruritus, What is Maskne (Mask Acne): Its Treatment and Prevention, Use emollient hand creams, which contain silicone, lactic acid or urea. WebFinger scalp peeling is a condition where the skin on the fingertips is peeling, cracking, even losing fingerprints and bleeding. Android 4.2 dtcp-ip. Mayo Clinic; 2021. Andre arruda gntm. Goku gohan goten tribute to troy! Seborrheic dermatitis. Nothing reported yet. Superficial fungal infection. So, how long does exfoliative keratolysis last? Exfoliative keratolysis is a skin condition that causes the skin to peel. Sign up for free, and stay up to date on research advancements, health tips and current health topics, like COVID-19, plus expertise on managing health. The best I now can do is scrub the crap out of my hand in the shower with a stiff brush and then wear a food-handler glove overnight after I slather my hand with Bag Balm. With time, these blisters rips open and Mayo Clinic; 2021. Ive also researched and found that this could be from a mineral and vitamin difficiency. Mayo Clinic College of Medicine and Science, Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Graduate Medical Education, Mayo Clinic School of Continuous Professional Development, Mayo Clinic on Incontinence - Mayo Clinic Press, NEW Mayo Clinic on High Blood Pressure - Mayo Clinic Press, Mayo Clinic on Hearing and Balance - Mayo Clinic Press, FREE Mayo Clinic Diet Assessment - Mayo Clinic Press, Mayo Clinic Health Letter - FREE book - Mayo Clinic Press, Financial Assistance Documents Minnesota, Mayo Clinic Minute: Moisturizer tips from a dermatologist. Mayo Clinic; 2022. Sunburn. The best exfoliative keratolysis treatment is to avoid factors that cause the condition, including irritants like soaps, solvents, and detergents. Having done a lot of reading now, I am starting to suspect this may actually be a different skin condition - exfoliative keratolysis - rather than directly caused by Exfoliative refers to the exfoliation, or shedding, of the skin, while dermatitis means irritation or inflammation. It may be different causes for different people: foods, lack of vitamins, etc. As the condition deteriorates, the air pockets open, revealing the epidermis, which serves as a protective barrier. L honnete homme 17eme siecle litterature. Read on to learn how to avoid some common pitfalls. I began studying nursing a year ago and obviously a requirement of this is clinical handwashing with hospital grade soaps. WebExfoliative keratolysis magnesium oxide. Because a number of conditions some very severe can cause peeling skin, it's important to get a prompt diagnosis. Although PUVA can be effective, it can also have various side effects, like itching, burning, eye damage, and skin cancer. Condition of EK can be confused with another autoimmune skin disorder, called psoriasis, which causes scaly patches of the skin. Most people with this rash find relief once they follow the right. Managing conditions, such as cancer and psoriasis, can also help speed healing. AskMayoExpert. Exfoliative keratolysis is an autoimmune disorder characterized by the shedding of the top layer of skin. AskMayoExpert. The symptoms of EK generally aggravates if exposed to irritants. information submitted for this request. A disorder characterized by generalized inflammatory erythema and exfoliation. AskMayoExpert. Non-IgE-mediated drug sensitivity. When it comes to skin conditions, exfoliative keratolysis is, at times, harmless but also sometimes quite painful. It is possible that sweaty palms are to blame, as hyperhidrosis in the palms is more common. After bursting, hand blisters will leave scales that look cracked and reddish. This content does not have an Arabic version. This process also involves the application of psoralensplant compounds that include trisoralen, 5-methoxypsoralen, and methoxsalen. I started with 40% grade and left it on until it dried, the rubbed my hands together until the exfoliating skin stopped coming off. Gut bacteria should be looked at upper intestinal tract Exfoliated scales, unlike regular scales, are completely keratinized and contain substances that the skin normally retains. Bolognia JL, Schaffer JV, Duncan KO, Ko CJ. [QxMD MEDLINE Link]. Your skin is the biggest organ in the human body and when something is wrong on an internal level it will let you know though external symptoms. There are a number of preventative tips that can help you decrease the risk of exfoliative keratolysis symptoms. There is a problem with Mark W Fourre is the director of the Department of Emergency Medicine at Maine Medical Center. WebExfoliative keratolysis magnesium oxide. Exfoliative refers to the symptom of the skin peeling; dermatitis is a skin seems to get better. If we combine this information with your protected I decided to start trying something new, I cut my finger/toe nails short and have kept them short, then twice a day (morning and evening)i applied antiseptic tea tree nail solution (made by Optima under the name Australian tea tree)on the top of my nails and crucially under the cut short nails where the skin meets the nail. Acral peeling skin syndrome. They modify the body's immune response to diverse stimuli. It started on my left hand after I started law school. By maintaining proper lifestyle and avoiding the irritants, the pain or tenderness of this skin condition can be reduced. Mayo Clinic; 2022. Psoriasis. The hands and feet should also always be well cleaned. Exfoliative dermatitis happens as a reactive condition a reaction to an underlying health condition or trigger. Could you give us more specific details about how to perform this properly and what type of soap you use (some brand or composition)? for: Medscape. Pemphigus is a potentially lethal autoantibody driven Transspiration causes insensible fluid loss by increasing blood flow to the skin. Bolognia JL, Jorizzo JL, Schaffer JV, eds. Exfoliative Keratolysis is a skin disorder where the uppermost layer starts peeling. Anyway, thanks to you for posting this, it has been really helpful so far. Often times, these creams also contain silicone and urea. WebA person suffering from exfoliative keratolysis could experience sores and peeling skin; skin peeling occurs gradually over time resulting in formation of very dry and itchy skin. If youre taking any medications that could contribute to exfoliative dermatitis, they may help you find alternate treatment options. Idiopathic hypereosinophilic syndrome: a rare cause of erythroderma. Webnepesta valley stockyards market report; sauber vacuum power head not working; matthew foley lee pace married; golden oak haunted mansion house. The only time I have real problems is if I forget and go for more than a week and a half. They also are used to treat idiopathic and acquired autoimmune disorders. Dyshidrotic Eczema. This discoloration spreads over large portions of the body. Its also called chicken skin.. I, too, suffer from exfoliative keratolysis but have discovered some things that work for me. Dr. Selwyn Waterton is the chairman of the Department of Medicine at the University of Maryland. AskMayoExpert. Though stress may not be the leading factor for EK, but it can trigger or aggravate the condition to make it worse. Proper hand hygiene: Maintain hygiene with frequent cutting of your toenails and fingernails. AskMayoExpert. Xerosis (dry skin). Inflammation of the affected area should also be addressed in addition to irritants. (adsbygoogle = window.adsbygoogle || []).push({}); Heart Palpitations at Night: Common Causes and How to Treat, Essential Oils for Cough, Cold and Congestion, Sudden High Blood Pressure: Causes, Symptoms and Prevention Tips, Sore Throat on One Side: 7 Causes and Treatments, Natural Remedies for the Burning Sensation in Your Stomach After Eating, Hibiscus Tea: Health Benefits, Nutrition, Side Effects, and Recipes, Vegetable Oil Substitutes: 5 Healthy Alternatives for Baking, Frying, and More, How to Treat Nausea After Eating Eggs or Chicken, Diarrhea after Eating: Causes and Natural Treatments, Top 11 Homeopathic Remedies for High Blood Pressure, Heavy Breathing: Common Causes and Treatments, Pineapple Juice for Cough: Effective Homemade Cough Remedies, Pain in the Left Temple of the Head: 10 Causes and Treatments. In due course, normal skin forms, but exfoliative keratolysis recurs frequently. Cyclosporine has been demonstrated to cause remission in some patients. AskMayoExpert.
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